All information is correct at the time of publication.
Date published: 1 July 2025
Click on the links in the age groups for more information about the disease each vaccine protects against.
8 weeks old:
12 weeks old:
16 weeks old:
12 to 13 months old:
2 and 3 years old and all school-aged children:
3 years and 4 months old:
School year 8 (12 to 13 years old):
School year 9 (13 and 14 years old):
Age 65 and older:
65 years and 70 to 79 years old (plus individuals from age 50 who are severely immunosuppressed)
Age 75:
| Age due | Diseases protected against | Vaccine and name | Usual site1 | |
|---|---|---|---|---|
|
8 weeks old |
Diphtheria, tetanus, pertussis (whooping cough), polio, haemophilus influenzae type b (Hib) and hepatitis B |
DTaP/IPV/Hib/ HepB |
Infanrix hexa or Vaxelis |
Thigh |
|
Meningococcal group B (MenB) |
MenB |
Bexsero |
Thigh |
|
|
Rotavirus gastroenteritis |
Rotavirus |
Rotarix |
By mouth |
|
| 12 weeks old | Diphtheria, tetanus, pertussis, polio, Hib and hepatitis B | DTaP/IPV/Hib/ HepB | Infanrix hexa or Vaxelis | Thigh |
| Meningococcal group B | MenB | Bexero | Thigh | |
| Rotavirus gastroenteritis | Rotavirus | Rotarix | By mouth | |
|
16 weeks old |
Diphtheria, tetanus, pertussis, polio, Hib and hepatitis B | DTaP/IPV/Hib/ HepB | Infanrix hexa or Vaxelis | Thigh |
| Pneumococcal | PCV | Prevenar 13 | Thigh | |
| 12-13 months old | Pneumococcal | PCV | Prevenar 13 | Upper arm/ thigh |
| Measles, mumps and rubella | MMR | MMRVaxPRO or Priorix | Upper arm/ thigh | |
| Meningococcal group B | MenB | Bexsero | Thigh | |
| 22 and 3 years old and all school aged children | Influenza (annually from September) | Live attenuated influenza vaccine3 | Fluenz3 | Both nostrils |
| 3 years 4 months old | Diphtheria, tetanus, pertussis and polio | dTaP/IPV | Boostrix-IPV or Repevax | Upper arm |
| Measles, mumps and rubella | MMR | MMRVaxPRO or Priorix | Upper arm | |
| School year 8 (12 to 13 year olds) |
Cervical cancer, some head and neck and ano-genital cancers, and genital warts caused by human papillomavirus (HPV) | HPV4 (one dose) | Gardasil 9 | Upper arm |
| School year 9 (13 and 14 year olds) |
Tetanus, diphtheria and polio | Td/IPV (check MMR status) | Revaxis | Upper arm |
| Meningococcal groups A, C, W and Y | MenACWY | Nimenrix or MenQuadfi | Upper arm | |
| 65 years of age and older | Influenza (annually) | Inactivated influenza vaccine | Multiple | Upper arm |
| 65 years of age | Pneumococcal (23 serotypes) | Pneumococcal polysaccharide vaccine (PPV) | Pneumovax 23 | Upper arm |
|
65 years old and 70 to 79 years old (plus individuals from age 50 who are severely immunosuppressed)5 |
Shingles | Shingles | Shingrix6 | Upper arm |
| 75 years old | Respiratory Syncytial Virus (RSV) | RSV | Abrysvo | Upper arm |
1 Where two or more injections are required at once, these should ideally be given in different limbs. Where this is not possible, injections in the same limb should be given 2.5cm apart. For more details see Chapters 4 and 11 in the Green Book. All injected vaccines are given intramuscularly unless stated otherwise. Check relevant Green Book chapters regarding co-administration of vaccines.
2 Children must be 2 years old by 31 August to receive influenza vaccine in the routine programme in autumn/winter.
3 If Fluenz is contraindicated, use a suitable inactivated flu vaccine.
4 Check the relevant chapter of the Green Book for individuals requiring a 3 dose schedule.
5 Refer to Green Book Chapter 28a: Shingles (external site) for further details and definition of severe immunosuppression.
6 Immunocompetent individuals require two doses of Shingrix with the second dose given 6 to 12 months after the first dose. Severely immunosuppressed individuals require two doses with the second dose given 8 weeks to 6 months after the first dose.
| Target group | Age and schedule | Disease | Vaccines |
|---|---|---|---|
| Babies born to hepatitis B infected mothers |
At birth and 1 month old1 |
Hepatitis B | Hepatitis B vaccines (Engerix B / HBvaxPRO) |
| Infants in areas of the country with TB incidence >= 40/100,000 | At birth | Tuberculosis | BCG |
| Infants with a parent or grandparent born in a high incidence country2 | At birth | Tuberculosis | BCG |
| People in a risk group for influenza3 | From 6 months to 64 years | Influenza | LAIV for children aged 2-17 years. Appropriate inactivated flu vaccine for people aged 18 years or older or if LAIV is contraindicated or otherwise unsuitable |
| Pregnant women | From 16 weeks of pregnancy | Pertussis |
Tdap (ADACEL) If ADACEL is unavailable or contraindicated, administer dTaP/IPV (Boostrix-IPV or Repevax) |
| From 28 weeks of pregnancy | Respiratory syncytial virus (RSV) | Abrysvo | |
| At any stage in pregnancy during the flu season | Influenza | Inactivated flu vaccine | |
| Gay, bisexual and other men who have sex with men |
45 years of age and under4 |
HPV4 | Gardasil 9 |
1 In addition to hexavalent vaccine (Infanrix hexa or Vaxelis) given at 8, 12, 16 weeks and 18 months. Take blood for HBsAg to exclude infection at 12 to 18 months.
2 Where the annual incidence of TB is >= 40/100,000 see the WHO country profile
3 Refer to annual flu Welsh Health Circular (WHC) for eligibility.
4 Check the relevant chapter of the Green Book for individuals requiring a 1, 2 or 3 dose schedule.
| Medical condition | Diseases protected against | Vaccines required2 |
|---|---|---|
| Asplenia or splenic dysfunction (including sickle cell and coeliac disease) |
Meningococcal groups A, B, C, W and Y
Influenza |
MenACWY Annual flu vaccine4 |
| Cochlear implants, cerebrospinal fluid leaks | Pneumococcal | PCV (up to ten years of age)3 PPV (from two years of age)3 |
| Chronic respiratory and heart conditions (such as moderate to severe asthma, chronic pulmonary disease, and heart failure) |
Pneumococcal
Influenza |
PCV (up to ten years of age)3 PPV (from two years of age)3 Annual flu vaccine4 |
| Chronic neurological conditions (such as Parkinson’s or motor neurone disease, or learning disability) |
Pneumococcal (only if the individual is also at increased risk of aspiration) Influenza |
PCV (up to ten years of age)3 PPV (from two years of age)3 Annual flu vaccine4 |
| Diabetes |
Pneumococcal
|
PCV (up to ten years of age)3 PPV (from two years of age)3 Annual flu vaccine4 |
|
Chronic kidney disease (CKD) |
Pneumococcal (stage 4 and 5 CKD) Influenza (stage 3, 4 and 5 CKD) Hepatitis B (stage 4 and 5 CKD) |
PCV (up to ten years of age)3 PPV (from two years of age)3 Annual flu vaccine4 Hepatitis B |
| Chronic liver conditions | Pneumococcal Influenza Hepatitis A & B |
PCV (up to ten years of age)3 PPV (from two years of age)3 Annual flu vaccine4 Hepatitis A & Hepatitis B |
| Haemophilia | Hepatitis A & B | Hepatitis A & Hepatitis B |
| Complement disorders (including those receiving complement inhibitor therapy) | Meningococcal groups A, B, C, W and Y Pneumococcal Influenza |
MenACWY |
| Immunosuppression due to disease or treatment | Pneumococcal Influenza Shingles |
PCV3 PPV3 Annual flu vaccine4 Shingrix (aged 50 years and over)5 |
1 The list is not exhaustive. Other vaccines may be recommended for certain individuals.
2 Check relevant chapter of the Green Book for specific schedule and for further detail.
3 See table 25.3 – Summary of vaccine doses for at-risk patients in the Green Book, Chapter 25: Pneumococcal for further information.
4 From six months of age.
5 Check Green Book Chapter 28a: Shingles for further information, including: definition of severe immunosuppression and interval for second dose.