Your antenatal blood test result: you are a beta thalassaemia carrier
This information is for you if you are pregnant and have had a blood test which shows that you are a beta thalassaemia carrier (often referred to as ‘having a trait’). This leaflet gives you information about being a carrier, and what this means for you and your family.
Published November 2025
Contents
― How your test result is written
― What your blood test result means
― Inherited haemoglobin conditions
― How would my baby inherit a Beta thalassaemia disorder?
― Should my baby's biological father be offered testing?
― What happens when my baby is born?
― Should I tell my family the result?
― Next steps and choices
― More information
How your test result is written
Your result is written as ‘results consistent with beta thalassaemia’.
What your bloods test result means
Haemoglobin is the substance in red blood cells that carries oxygen around your body. Being a beta thalassaemia carrier means you have inherited one usual haemoglobin gene called haemoglobin A from one biological parent and one beta thalassaemia gene from your other biological parent. Because you have inherited usual haemoglobin A from one parent, you are healthy. Being a carrier does not make you ill.
As a beta thalassaemia carrier, your red blood cells are smaller than usual and your haemoglobin level is lower than normal. This is different to iron deficiency anaemia. Before taking iron supplements always ask your healthcare professional to check your iron levels. Knowing that you are a beta thalassaemia carrier means that you could pass the beta thalassaemia gene on to your baby. If your baby’s biological father is also a carrier, this means together you could have a baby with an inherited haemoglobin condition.
Please let your healthcare professional know if you:
• became pregnant following fertility treatment with donor sperm or a donor egg;
• have had a bone marrow or stem cell transplant; or
• are pregnant as a surrogate.
Inherited haemoglobin conditions
Haemoglobin conditions are blood disorders inherited from both biological parents. There are many haemoglobin conditions. The type of condition your baby could inherit will depend on the haemoglobin genes both biological parents have. Some conditions are more serious than others such as sickle cell disorders and transfusion dependent thalassaemia (thalassaemia major).
Your healthcare professional can discuss this with you, so that you understand what condition your baby could inherit and how this could affect the health of your baby.
How would my baby inherit a Beta thalassaemia disorder?
One biological parent is a carrier and the other is not
If your baby’s biological father has two usual haemoglobin genes (AA), there is a 2 in 4 (50%) chance your baby will be a beta thalassaemia carrier (like you) and a 2 in 4 (50%) chance they will have two usual haemoglobin genes (AA).
See diagram below. These chances are the same in every pregnancy for this couple.
What if both biological parents are carriers?
If your baby’s biological father is also a carrier, there is a 1 in 4 (25%) chance your baby will inherit a haemoglobin condition. The seriousness of the condition will depend on what haemoglobin genes are inherited.
There is also a 2 in 4 (50%) chance your baby will be a carrier (like you) and a 1 in 4 (25%) chance your baby will have usual haemoglobin genes (AA).
See diagram below. These chances are the same in every pregnancy for this couple.
Should my baby's biological father be offered testing?
If your baby’s biological father has an unusual haemoglobin gene it is important to identify the type of gene and the chance of your baby inheriting a haemoglobin condition. For this reason, we will also invite the biological father for screening. He will only know if he carries a gene for unusual haemoglobin if he has a blood test to check his haemoglobin type.
If the test shows your baby’s biological father is a carrier of an unusual haemoglobin gene you will be offered specialist counselling prenatal diagnosis.
What happens when my baby is born?
All babies are offered a newborn bloodspot screening test around four days after their birth. This test will screen for sickle cell disorder.
Should I tell my family the result?
Other family members, such as brothers and sisters, aunts, uncles and cousins, may want to consider getting tested as they could be carriers too. Sharing this information with them may be helpful.
Next steps and choices
You can also:
• let your GP or healthcare professional know you are a beta thalassaemia carrier; and
• contact All Wales Medical Genomics Service (AWMGS) where you can get free information and advice to help you understand the implications of being a beta thalassaemia carrier.
• You can donate blood (when not pregnant) as long as you are not anaemic (do not have a lower haemoglobin than usual).
• Donating blood - Welsh Blood Service
More information
You can get more information from the following:
NHS 111 Wales - Health A-Z : Thalassaemia