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Quarterly COVER report: October to December 2025

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Authors: Vaccine Preventable Disease Programme

Published on: 31st December 2025

  • Quarterly COVER

The quarterly COVER report summarises immunisation uptake in children in Wales reaching key birthdays between October to December 2025.

Key points from Quarterly COVER Report 157

Age Immunisation Uptake (%)
1 year 6 in 1 primary (3rd dose) 93.0
1 year MenB (2nd dose) 93.1
1 year Rotavirus primary (2nd dose) 90.8
1 year PCV primary (1st dose) 94.6
2 years MMR (1st dose) 92.5
2 years PCV (final (3rd) dose) 92.5
2 years MenB (3rd dose) 92.1
2 years Hib/MenC booster 91.2
4 years Up to date with all routine immunisations 85.1
5 years MMR (2nd dose) 89.2
5 years 4 in 1 pre-school booster 89.1
5 years Up to date with all routine immunisations 87.5
School year 8 Human Papillomavirus Vaccine (HPV) (one dose) 10.6
School year 9 Human Papillomavirus Vaccine (HPV) (one dose) 71.3
School year 9 MenACWY 20.0
School year 9 Td/IPV teenage booster 20.4
School year 10 Td/IPV teenage booster 73.2
School year 10 MMR (1 dose) 96.0
School year 10 MMR (2 doses) 93.2
School year 11 MMR (1 dose) 95.8
School year 11 MMR (2 doses) 93.5

General information about the diseases which each vaccine provides protection against is available on the NHS 111 Wales site.

Bar chart titled “All Wales Summary – COVER 157,” showing vaccination coverage percentages for different immunisations by age. Most measures are in the 89%–96% range and shown in amber. Highest coverage is MMR (1 dose) by age 16 at 95.8%, followed by PCV (final dose) and MMR (1 dose) by age 2 at 92.5%, and the 6-in-1 primary series at 93.0%. Lower-performing measures are highlighted in red: MMR (2 doses) by age 5 at 89.2%, 4-in-1 pre-school booster at 89.1%, Teenager booster at 75.8%, and MenACWY at 75.7%, indicating notably lower uptake among older children.

Maps indicating the uptake of the 6-in-1 vaccination by one year of age and the uptake of the MMR1 vaccination at two years of age in HB resident children for the most recent quarter are given below:

Map of Wales showing percentage uptake of the 6-in-1 vaccine by age 1 across local areas, colour-coded into three bands. Most of Wales is shaded orange, indicating uptake between 90% and 95% (12 areas). A single area in the north‑west is shaded light green, representing higher uptake of 95%–100% (6 areas overall). Several areas are shaded red, indicating lower uptake below 90% (4 areas), including a large area in the south‑west and smaller clusters along the south coast and south‑east. A legend in the bottom left explains the colour bands: green (95–100), orange (90–95), and red (0–90). Map of Wales showing uptake of the first dose of MMR vaccine by age 2 across local areas, colour-coded into three bands. Most areas are shaded orange, indicating uptake between 90% and 95% (16 areas). Three areas are shaded light green, representing higher uptake of 95%–100%, forming a band across the central and western parts of Wales and a small area in the south‑east. Three areas are shaded red, indicating uptake below 90%, including a large area in the north‑east, a coastal area in the far south, and a smaller neighbouring area in the south‑east. A legend in the bottom left shows the categories: green (95–100), orange (90–95), and red (0–90).
6 in 1 uptake by 1 year of age 1 dose of MMR uptake by 2 years of age

The trends chart below, shows uptake of selected routine childhood immunisations in Wales resident children, as reported in the Public Health Wales Quarterly COVER reports from 1997. Uptakes of vaccinations against diphtheria, tetanus, pertussis, Hib, MenC and PCV2 are presented for one-year-old children. Uptake of the first dose of MMR and the Hib/MenC are presented for two-year-old children. Uptake of the second dose on MMR is presented for five-year-old children.

Line chart of vaccination uptake in Wales (1999–2025) showing most vaccines near 90–95%, with recovery after early‑2000s dips, but recent declines in some measures, especially the teenage booster dropping to around 75%.

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Quarterly COVER report - October to December 2025

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