3rd Generation Cephalosporin Resistance in Wales 2014
Published on: 6th October 2020
- All Wales/National
All Wales 3GC targeted surveillance study
Carbapenem resistance in Gram-negative bacteria is an increasing problem across Wales and the World, resulting in treatment failures and contributing a significant risk to the patient. Third generation cephalosporin (3GC) resistance in Gram-negative bacteria drives carbapenem use and may contribute to increasing levels of resistance.
It is therefore important to determine the levels of 3GC resistance in Gram-negative bacteria; every 5 years SACU will collect a cross section of 3GC resistant Enterobactericeae strains isolated in Welsh laboratories and investigate the mechanisms of resistance.
In 2008 and 2014 SACU collected approximately 1/6th of all 3GC resistant Enterobacteriaceae across Wales. Details of the 2014 collection can be seen in the reports below. We are currently collecting strains isolated during 2020 to 2021. Next collection is likely to be 2025 to 2026.
Table of contents:
2020 surveillance
We would like to continue our surveillance of 3rd generation cephalosporin resistance in Wales by asking all laboratories to submit the following isolates to SACU:
| Hospital Location | No. Requested | Hospital E.coli | Hospital Coliform | GP E.coli | GP Coliform |
| Bronglais Hospital, Aberystwyth | 32 | 6 | 4 | 17 | 5 |
| Royal Gwent, Newport (incl. Royal Glamorgan) | 196 | 39 | 62 | 54 | 41 |
| UHW, Cardiff | 169 | 48 | 29 | 68 | 24 |
| Singleton, Swansea | 226 | 25 | 90 | 27 | 84 |
| WWGH, Carmarthen | 129 | 26 | 30 | 36 | 37 |
| Ysbyty Glan Clwyd, Rhyl (incl Maelor & Bangor) | 259 | 62 | 45 | 102 | 50 |
| Total | 1011 | 206 | 260 | 304 | 241 |
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3rd Generation Cephalosporin Resistance in Wales 2014
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